calliecritturs
Posted : 12/30/2006 2:02:13 PM
The dose of Benedryl for common 'home' useage is 1-2 mg/lb body weight two to four times a day (i.e., not the dose for something like anaphylactic shock that a vet may push to save a life). The over-the-counter pills are 25 mg typically. (and it has to be plain benedryl/diphenhydramine NOT "severe cold formula" or something like that).
The 1 mg/lb dose is what I use most of the time, and I wouldn't use the 2 mg/lb dose for long term because it can get a bit hard on the kidneys. 1 mg/lb is far more than the human dose but dogs have a faster metabolism which in the case of Benedryl/diphenhydramine is why it takes more for dogs. When you get to a bigger dog in particular the dose sounds huge. For a 100 pound lab that's four capsules at once for a minimal dose. And a 250 pound human might get knocked flat by one pill.
Each antihistamine is dosed differently. You can find a veterinary PDR at most libraries, and my copy of "The Pill Book Guide to Medications for Your Dog and Cat" (Dell reference, 199

is one of my best reference tools.
Tavist is now typically said to be the 'best' antihistamine for dogs. The dog I tried it on reacted badly to it (he actually had a bona fide 'allergic reaction' to it my vet said) but that's just one dog out of many.
The sleepy/calming effect of Benedryl IS a big plus -- often it will help break the cycle of itching just for that reason.
No one is gong to "take home" 10 different meds at once -- you try something. And then you try something else if that doesn't work. And most people don't even know what you can use. A lot of vets use hydroxizine just because some people have more' confidence' in something prescribed by the vet and it's virtually not used at all in people any more (it can have some severe emotional reactions in people - it's an older antihistamine from the same circa as diphenhydramine).
The thing in dogs that causes the paw-licking and biting is the histamines that settle at the surface of the skin -- it makes tingles (not unlike if you set on your foot too long and you get a tingly foot from poor circulation). I will often use the homeopathic "hypericum" specifically to help alleviate that symptom no matter what else I'm doing for the allergies.
A lot of times when someone says "it doesn't work" -- they were expecting a total and complete cessation of the symptoms -- if it doesn't completely eradicate the symptoms they don't think it's working. But often with allergies you have to do several things to help (with humans too unfortunately).
Dogs absorb environmental, atopic allergens both from their skin surface/feet and also thru the mouth/nose. They have a whole extra organ of smell - the Jacobsen's Organ -- which is a SUPER filter for allergens and typically allergens can become trapped in there and take weeks to work their way into the bloodstream and 'out' of the body. In honesty, I've never found 2 weeks to be a fair 'trial' for any antihistamine. I've heard a few vets say that but since it can take a week or better for an environmental/atopic allergen to come OUT on the skin/mucus membranes it doesn't seem sensible to me that 2 weeks is a long enough trial because what the dog is 'reacting' to TODAY may be what he breathed in last week -- and if part of the function of an antihistamine is to give the body the tools to deal with allergens as they *enter* the body then what the dog sniffs in today won't 'show' as being effected by that anthistamine for a week when 'less' reaction should be noted.
Then we're back to what I said -- 2 weeks is often not enough to know if something IS helping. I know I have to use benedry AND Bathing AND homeopathics AND immune-boosting on Billy and that's not even counting the thyroid meds he takes to help body balance from that standpoint. And he STILL breaks out -- but we keep it minimal.
I've had six major allergy dogs now -- and they've all reacted differently. Billy is by far the worst sufferer, but I've also thankfully learned a thing or thirty about helping him deal with them. But I've had the most success with his ear-allergy-related problems than any of the prior dogs. And this is a dog who came to me 2 1/2 years ago with his ears swelled SHUT from atopic allergies and they are now sparkling clear and have no 'problems'. (however, I just 2 minutes ago put zymox in his ears today -- as I do every single day -- to help his body keep those tissues healthy enough not to react to the allergies.
When he was first treated for the IMHA and they were ruling everything out -- they took him off Benedryl -- and within 2 days he had his paws a MESS and he was pawing at his ears madly within a week. Benedryl doesn't completely take care of all his symptoms but it 'helps'.
I cook for him -- so grains and additives are minimal, but food is a lesser issue with him - I've proved it over and over. And he's a 52 week a year allergy boy. Then again -- I'm in Florida. Worst state in the union for allergies I think. (and that's MY allergies talkn *sigh*).