Desperate, Please Help

    • Silver

    Desperate, Please Help

    We have two golden retrievers, one is a 20 month old male and the other is a 7 month old female. The male is 90 pounds, the female 40. Both came from the same breeder.

    The male started having seizures just after his first birthday. He would seize 2-3 times a night, exhibited really frantic behavior, and we were left wondering where our sweet, gentle pup had gone. He was not neutered due to an undescended testicle that we were waiting for, and since he started seizing anesthetic and thus surgery is out of the question.

    Anyway, after several thousand dollars in vets, drugs, etc. we finally got his seizing under control. He did lose upwards of 20 pounds at one point, stopped eating altogether, and was generally on death's doorstep. The breeder was devastated and gave us a puppy left from a recent litter as we thought we'd have to put our male down.

    After getting the puppy, he suddenly turned around. Now several months later, he is the picture of health though he does get phenobarb twice a day. He is a gorgeous dog and from looking at him you'd never think anything was wrong.

    The root of his seizing, digestive issues, and elevated white blood cell counts is still undiagnosed. He continues to have abnormal bloodwork. He also has bladder control issues and will urinate on himself during sleep.

    The problem that we have-- in the last several months, he has gotten extremely aggressive. Our female is afraid of him, and there are days when I am too. It is like he has lost the ability to censor himself. There is no sense of boundaries in his mind. Our neurologist described him as "juvenile," and our female has passed him in maturity. He will jump, bite and not release-- he has done this to my arm on several occassions, and he nearly caught my face this afternoon.

    He will go after our female even when she is in the most submissive of positions. Friends and family no longer come over, they are afraid of him. He is impossible to contain as he goes ballistic in his crate if any kind of activity is going on around him. He becomes hyperactive even with a small bit of stimulation. He has on many occassions knocked grown men over.

    We have devoted our life and our money and our energy to saving this dog and getting him back to optimum health. Obedience classes have no effect. We have tried every technique under the sun. I am convinced the behavior issues stem from the seizing, and that there is some underlying issue whether it be a brain tumor, imbalance, or brain damage.

    I have had dogs and horses my whole life and have never encountered such an issue. I don't know what to do and am afraid we have no options but one we were hoping to avoid. Any and all advice, suggestions, input would be appreciated.
    • Gold Top Dog
    What a horrible thing to happen to you, and your dog.  My gut feeling is that the aggression is related to his siezures, perhaps talking to the vet/specialist about increasing or changing his medication.  Perhaps look into Potassium Bromide?  I've also heard about a few other drugs that are $$$, but don't know the names of these drugs off the top of my head.  (Seems like the person had to get them from a human pharmacy.) 
     
    I'd also look into taking him completely off grains, as I know of several cases where dogs who have been taken off grains have decreased their siezures or become siezure free. 
     
    While he's a bit young for thyroid problems, I'd have a complete thyroid pannel done from MSU or hemopet.  (NOT in-house stuff.  Don't let the vet tell you different if you're going to have it done.)
     
    Also I've heard about a lab whos sudden aggression was traced back to lymes disease.  (I'm pretty sure it was lymes.  I know it was a tick born disease.)
     
    And if you haven't done so, I'd get the female spayed if your boy can't be neutered.  This will make life easier on you and him.
     
    Good luck and please keep us posted.  I think you'll find this community can be very supportive of people who care as much about their pets as you do.
     
     
    • Gold Top Dog
    This really does sound like agilebasenji is on the right track about it being a physical problem resulting in abnormal behavior.
    Do talk to your vet, but before you make any final decisions, consider also consulting with a homeopathic or holistic veterinarian.
    I had a student whose dog was seizing multiple times, and the holistic vet gave him belladonna - no more seizures.  Not saying that will help your dog, but it is worth the consultation IMO. 
    • Silver
    Hi there Agilebasenji & Spiritdogs....

    I do strongly believe that there is a medical basis for the hyperactivity and aggression issues, as he seems to lack the normal capacity to respond to any sort of training methods.

    I have heard something about grains before, I will look into that further.

    My first call tomorrow morning is to the vet. Going to see if we can possibly think about reducing the phenobarb. Maybe its the meds causing the behavior issues-- I have heard from our neurologist that when their bodies get used to a certain dosage, it is enough to cause "invincibility" type feelings similar to that in a person who is "buzzed" on alcohol. It's like enough to alter their mindstate but not enough to make them dopey.

    We did spay our female right away, didn't want any in-bred puppies (or any puppies at all!) considering they are full brother and sister! :)

    We are so reluctant to give up on him, we have gotten him this far. We are just becoming increasingly concerned for our safety, our other dog's safety, and that of people who may wander into the yard. And it is a bit sad that friends and family will no longer come to visit!

    In any case, I appreciate the thoughtful responses!
    • Gold Top Dog
    You can acclimate him to wearing a muzzle until you solve this - at least it will keep everyone safe, including your dog.  If you do that, be sure you keep dogs separated if they tend to play - a tooth or a nail caught on someone else's muzzle ain't a pretty sight.
    I commend you for trying to do all you can to attempt to solve this dog's problem.
    • Silver
    The muzzle idea is excellent, and something we will discuss w/ the vet, it could be a good solution and at least keep us out of harm's way until we can get his behavior back under control.

    Thanks again for the responses, I really appreciate the input.
    • Gold Top Dog
    A BASKET (racing) muzzle would be the best kind to use in this situation. I wouldn't use the kind of muzzle that holds his mouth shut, as it will hinder his ability to breathe properly (can't open his mouth to pant) and he won't be able to wear it for long. 
    • Gold Top Dog
    Have you thought about having a CAT Scan or MRI, it sounds like a brain issue, maybe he has a tumor or something that could cause both the seizures and the agression.  If he wasn't agressive before, maybe something is pushing on his brain to cause this.  I would ask the vet.
    • Silver
    Hi there.... my vet originally thought brain tumor, but the neurologist said our dog wasn't presenting w/ typical symptoms.

    Agilebasenji, I was doing some research this afternoon and came across study published by Dr. Jean Dodds about thryoid issues. Our dog has exhibited MANY of the behavioral and medical symptoms she mentioned. I don't believe we've had a completed thyroid panel done, at least not to my knowledge.... it is something I will be asking the vet about when the dog goes in this week.

    • Gold Top Dog
    ShandyNBeau-
     
    I don't want to give you false hope, but hypothroidism is soooo easy to take care of - one pill twice a day.  And hypothroidism is very, very common in goldens.  And I'll say this again because I don't think it can be stressed enough, you need a COMPLETE pannel, not inhouse.  Sent to hemopet (Dr. Jean Dodds) or MSU.  I'd go to another vet if he insisted on sending it somewhere else.  After you get your results, talk to your vet and if you still have questions, send the results to Dr Dodds.  She, while not always available as she is an indemand speaker, is always willing to help and very generous with her time.  (Gosh, that would be so great if he's HP.)
    • Silver
    I hear ya, I am trying not to get hopeful, but really it would be great if that was all that was wrong. Considering everything we have dealt with it'd be amazing if we could get him on some meds that truly made a difference.

    Thanks for the info on the testing, I will be sure to discuss with the vet. Earliest appt. I could get was saturday so we'll see how it goes.....

    • Gold Top Dog
    We'll keep our fingers and paws crossed for you.
    • Gold Top Dog
    All fingers and paws crossed here too!  Sorry I have no info for you but you have our thoughts and prayers.
    • Gold Top Dog
    Poor little dog.  And poor you, how stressful this must be.  Please keep us posted. 
    • Silver
    Thanks all for the good wishes. We need them!