Posted : 3/25/2008 4:03:12 PM
1) an example of C interfering with/exacerbating bone-related problems from Cornell:
Ascorbic acid deficiency and hypertrophic osteodystrophy in the dog: a rebuttal.
ascorbic acid (PAA) in normal Labrador Retriever dogs less than one
year of age averaged 1.22 +/- 0.05 mg/dl (x +/- sem) and was
significantly higher than the value of 0.89 +/- 0.03, for Labrador
Retrievers two years of age and older. No significant diurnal variation
in PAA was observed. Oral or intravenous administration of 0.5 or 1.0 g
of ascorbic acid (AA) elevated PAA for less than 8 hours. Injection of
ACTH caused a significant decline in PAA for the initial 2 days, with
variable results thereafter. Labrador Retriever puppies fed a ration
high in protein, energy and calcium developed the typical skeletal
diseases of overnutrition, including hypertrophic osteodystrophy (HOD).
The addition or oral AA (0.5 g twice daily) had no ameliorating effect
on the skeletal lesions. Instead AA supplementation resulted in
relatively higher serum calcium values which, presumably by enhanced
hypercalcitoninism, decreased bone resorption. Thus, AA treatment of
dogs with HOD is contraindicated, as it can only aggravate the osseous
lesions of HOD. The decreased PAA reported in dogs with HOD is
interpreted to be the result of stress from pain.
I was also told this my by school's leading orthopedic broad-certified surgeon, if you want to play the name game
Vitamin C *is* indicated in times of stress and inflammation, such as post-surgery.Which is why your surgeon suggested it post-TPLO. What I was referring to was feeding a growing dog excess C. The reason Cosequin, etc are indicated is to reduce inflammation caused by *current* bone problems. That is what the C is for.
Just because your breeder uses is and her dogs have healthy hips doesn't mean it prevents hip dysplasia, etc. Her dogs should be genetically free of HD and orthopedic problems anyway, so feeding extra C would not have such a deleterious effect as it would in a young, at risk dog. But I don't see why you woudl take the risk, when the only scientific data around (do a pubmed searchy) indicates that C decreases bone remodeling.
Most likely mainstream Vet. Medicine Pooh Pooh this Vit. C stuff.
Bleh, I can't tell you how sick I am of hearing this. As if by definition, if you're in the veterinary world you're some silly old fart who refuses to progress. Again, mainstream vet med does not pooh-pooh Vit C for correct usage - i.e. for inflammatory conditions and healing - not for orthopedic function in a growing dog. The research does not support it.
Lastly, excess C is eventually eliminated from the body. But the body can still absorb quite a bit of extra before things are saturated. It is almost impossible to "overdose" but it IS possible to have the body absorb more than what it currently requires and needs.