Nikko Bo
For those of you with dogs that have been treated for IMHA and made it I am curious to know how long has it been since diagnosis, what was the red blood cell count at the time of diagnosis and how much has the treatment cost totaled so far? How many have dogs that have relapsed?
Billy was first diagnosed in June, 2006. At first they did prednisone. His timetable was a bit unusual:
1. mid-June -- he seemed "just didn't feel well" and I took him to the vet for bloodwork (had been a while and needed to do senior bloodwork ANYWAY). Saw just a tiny evidence of nausea (didn't want to jump on the waterbed, etc ... nothing major but not "typical";).
Bloodwork came back with a hematacrit of 20. WHOA!! The vet immediately put him on a big dose of pred JUST IN CASE.
We did a tick test immediately BECAUSE I knew he'd been bitten about 6 weeks prior. Got a very FAINT positive.
While waiting for the tick test to come back, I had his blood checked (just a 'pack cell' not a whole blood panel) and it had climbed to 29 !!! RAH!!!
That was about two weeks after that first 'crit of 20 by the time all these tests were done and came back. Vet called me with the "faint positive" results on the test, so he recommended adding doxycycline. So his pcv was 29 and it was Wednesday and we added the doxycycline in the evening of that day.
By Friday (not quite 48 hours later) when my husband walked in that evening, Billy got up to go 'greet' him and STAGGERED. We literally grabbed keys and my purse and his leash and walked out the door to the e-vet. In just that 48 hours since the pcv was seen at 29, it had plummeted to TEN !!!!!! A drop of 19 points in less than 48 hours.
Because my vet had already diagnosed IMHA potentially triggered or exacerbated by tick disease AND Billy was already on prednisone (big dose), the emergency vet simply transfused him because it was so low. That was like 11:00 p.m. (the night he staggered when David came home) and we picked him up about 5:30 a.m.and went sailing up to the vet at 7:30 a.m.
After he got the blood his PCV was back up to about 24. That was Saturday morning.
By Monday it was back down to 12 by 8:00 a.m. and my vet sent me straight to Gainesville (University of Florida).
That was the "beginning" of Billy's onset and treatment. Billy had a total of SIX transfusions over the next month.
Like Cyclops they did a bone marrow draw and in Billy's case his body was killing the baby red blood cells in the bone marrow. That's why it took so long to respond.
NOTE:
1. The faint positive tick test was sort of a red herring. It was NOT accurate. It wasn't a positive at all but rather the test read **antibodies** that had been formed as that mild positive.
2. That means that the doxycycline that we gave him HURT - it didn't help. The antibiotic actually TRIGGERED the IMHA to go into overdrive.
THIS IS ***NOT*** typical. this IS what happened to my dog tho -- and honestly it wasn't until a month later when we got the findings back on a huge tick PANEL that they did (that darned thing was over $1000 itself) that we were able to completely rule OUT tick disease and take him off the doxycycline.
In short, Billy began to respond AFTER we took him off the doxycycline. Now -- we'll never know. Did his body finally just get saturated *enough* with cyclosporine (Atopica is the dog brand) to finally completely suppress the immune system, OR was the doxycycline just exacerbating the whole thing and triggering the immune system to just keep on beating up the blood???
All I know is once we took him OFF the doxycycline he began to turn around.
COST???
Frankly, it's almost impossible to calculate. For several reasons:
1. His wasn't typical because of the whole tick disease/doxycycline thing -- that may have actually exacerbated this enormously -- we'll never know.
2. While he was up at UF Gainesville -- he was In/Out of ICU for the better part of 3 weeks out of 4. (up for 5 days home for 2, up for 4 days home for 2, etc.) THAT was pricey -- ICU is pricey period.
3. Gainesville is 3-4 hours away from where we live so do I factor in how much it cost me in gas and motels? and being gone from work??
4. We also opted to have him treated with acupuncture and Chinese herbals (right AT the University of Florida -- they teach acupuncture and Chinese herbals *there*). So that was extra expense but it also likely helped his body respond and regenerate blood *enough* to keep him alive.
5. Billy is a buffy coated English cocker. English cockers are HARD-WIRED ***NOT*** to respond well to treatment for IMHA. There are some breeds that are notorious for NOT responding and English cockers specifically are a breed with a huge mortality rate for IMHA.
Further -- there is somethig genetically related about the buffy coat -- I was told again and again TO EXPECT fatality because buffy coats just did *not* respond well and usually died.
to this day, in all the internet trolling I've done, I know of only one other buffy coat English cocker to have survived IMHA.
6. We opted to have them use Atopica (the dog formulated version of cyclosporine - you can NOT use human cyclosporine on a dog).
Atopica is fiercely expensive. But it tends to have a higher response rate than azathiaprine or some of the other used. For example -- a month's worth of azathiaprine for Billy would have been about $25.00. A month's worth of Atopica?? Was about $800
Yeah --a house payment! Then the dose was reduced eventually but he stayed on the high dose of cyclosporine for 7 months ($5,600 just for Atopica). That would have compared to $150 for azathiaprine.
I didn't pay quite that because my vet ordered the Atopica for us at his cost.
6. Because Billy had some mega side effects (major huge urinary tract infections and stomach ulcers) I wound up having to use other meds and supplements that were incredibly pricey to deal with the side effects.
HOW did we afford it?
A. Billy is a therapy dog -- I couldn't face telling the parent of a child helped by Billy that I didn't want to afford his treatment. SOOOOOOOOOOOOOOOO
B. We had gotten a settlement that was significant AND I had not touched my Christmas bonus for the past several years. We aren't independantly wealthy -- but for THIS illness we were willing to spend the money. I still have the same ratty drapes up that were in this house when I moved in 23 years ago.
SO my point is?? We were willing to cut corners in other areas in order to do this for Billy. We have no children -- and we were both willing to drive older cars and "make do".
BUT PLEASE REMEMBER:
It's not just A + B = C.
Billy's case was complicated by other things. I don't know of ANY case yet where anyone knew UP FRONT what the ultimate cost would be. It's a matter of making the best guess you can, and then how willing you are to sacrifice or borrow or whatever to take the next step.
Some folks can NOT do that. That doesn't mean they are bad -- it's just their situation.
I wish I had kids. I've never been ABLE to have them. These dogs ARE my "kids". Each one of them give's back in huge measure because they are all therapy dogs (or in training to be).
But what it cost for MY dog isn't at all what it might have cost for YOUR dog. PLEASE understand that. Because of his breed, because of the distance, because of the false tick diagnosis -- those things made Billy different.
then in addition, we were also willing to spend the extra money to protect his body (with the tons of milk thistle) and the Chinese medicine to help minimize the damage.
Because of his breed it took us EIGHTEEN MONTHS to wean him off all the drugs. That's not typical. Again.
so ... this is why I never break out the cost of what Billy's cost. It's not fair -- it mis-represents to other people what their dog might incur.
Billy has never actually relapsed but he has had a few 'scares'.
YOu won't know how many relapsed -- because most of the time when a dog relapses it dies and frankly, people in that situation often just don't hang around here.