Gail
Posted : 4/4/2006 8:41:58 AM
OK - well, the above link for the AVMA is bringing up a blank page, so, I'll copy & paste but for those of you that have a memebership, you can access the entire study.
Abstract
American Journal of Veterinary Research
February 2004, Vol. 65, No. 2, Pages 138-142
doi:10.2460/ajvr.2004.65.138
Evaluation of effects of dietary carbohydrate on formation of struvite crystals in urine and macromineral balance in clinically normal cats
Dr. Masayuki Funaba, PhDAkira Uchiyama, BSKen-ichiro Takahashi, DVMMasahiro Kaneko, BSHiromi Yamamoto, DVMKazuhiko Namikawa, DVM, PhDTsunenori Iriki, PhDYoshikazu Hatano, BSMatanobu Abe, PhD
Laboratory of Nutrition, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Sagamihara 229-8501, Japan. (Funaba, Uchiyama, Takahashi, Namikawa, Iriki, Abe); Research and Development Center, Nihon Nosan Kogyo K. K., 5246 Takura, Tsukuba 300-2615, Japan. (Kaneko, Yamamoto, Hatano)
Objective—To evaluate effects of dietary carbohydrate on urine volume; struvite crystal formation; and calcium, phosphorus, and magnesium balance in clinically normal cats.
Animals—21 healthy adult cats (15 sexually intact males and 6 sexually intact females).
Procedure—Diets containing no carbohydrate source (control diet), control plus starch, or control plus fiber were given in a 3 × 3 Latin-square design. The diets were available ad libitum in study 1 (n = 12) and given under restrictions in study 2 (9) to equalize daily intakes of crude protein among the 3 groups. Formation of struvite crystals and balance of calcium, phosphorus, and magnesium were measured.
Results—Urine volume was lower in the starch group and fiber group in study 1, whereas no differences were detected among the groups in study 2. Urinary pH and struvite activity product were higher in the starch group in both studies, and the fiber group also had higher struvite activity product in study 2. In both studies, urinary concentrations of HCl-insoluble sediment were higher in the starch group and fiber group. In the fiber group, a net loss of body calcium, phosphorus, and magnesium was detected in study 2.
Conclusions and Clinical Relevance—Starch and fiber in diets potentially stimulate formation of struvite crystals. Hence, reducing dietary carbohydrate is desirable to prevent struvite urolith formation. In addition, a net loss of body calcium, phosphorus, and magnesium during feeding of the fiber diet suggests that dietary inclusion of insoluble fiber could increase macromineral requirements of cats. (Am J Vet Res 2004;65:138–142)