frontline reaction

    • Silver

    frontline reaction

    yesterday applied topical frontline to my sharpei, used advantage before, anyway, today she has been pretty lethargic, breathing ok, just sleeping alot, off her feed & water somewhat. wondering if possibly she is having reaction to frontline.

    • Gold Top Dog

    I'ld be going to the vet if I were you.  Everytime I see someone say they used frontline and thentheir dog is showing signs of lethargy might be a sign of anemia.  The only reason I say this is because it's a known trigger for anemia. 

    In either case keep a good eye on Sharpei and watch for pale gums etc.

    Vet sounds ideal though.

    Johnny & Tessy

    • Gold Top Dog

    She is ABSOUTELY right.  Frontline is honestly one of the safest flea preparations out there ***BUT*** it can be a trigger (not a 'cause' but literally just the dominoe that triggers it) IMHA -- a/k/a immune-mediated hemolytic anemia.

     Go **now** and look at your dog's gums.  Please do NOT wait. (and I'm going to email you as well just in case you don't see this right away).

    IF the gums are pale go to an emergency vet **RIGHT AWAY** -- don't even wait for tomorrow.  Don't try to "think about it" -- Johnny and I are very very well acquainted with this (far too much so, eh my friend?)

    IMHA is treatable if you get it right away.  But "lethargy" is often the first symptom and it is so easily rationalized. 

    There are many, many other triggers for IMHA, but a chemical, or toxin can often be the ultimate thing the body zeros in on. 

    there are other auto-immune diseases that are similar (thrombocytopenia, pancytopenia, and others0 -- but essentially the body turns against itself and begins to destroy its own blood.  hence the anemia. 

    I hope I'm simply pushing your buttons for nothing -- but when you get a reaction like that to Frontline it's sometimes the ONLY sign you get of the deeper problem afoot.

    • Gold Top Dog

    Exactly what Callie said!  Better to be safe than sorry. 

    • Gold Top Dog

    In the almost 4 years that I worked at the front desk of a veterinary hospital, and have done follow up phone calls...I can not remember even one pet with a reaction to Frontline. However that said....of course I believe there could be.

    So first...hopefully you listen to Callie and do what she said as a start.

    Second...I hope your dog is okay.

    But as a person that has worked with a group that watches adverse reactions in pet supplies/meds......if you do suspect that this is a reaction to Frontline, PLEASE PLEASE PLEASE report it to the FDA. and while looking for how to do that I came across this on the Adverse Reaction site:

    If you suspect your pet had an adverse reaction to a pesticide product, please contact:

    U.S. Environmental Protection Agency
    Office of Pesticide Programs (Mail Code 7509C)
    Ariel Rios Building
    1200 Pennsylvania Ave. NW
    Washington, D.C. 20460

    E-mail: opp-web-comments@epa.gov

    Also see this link: http://www.dogsadversereactions.com/fdasuspect.html

    • Gold Top Dog

    When I talked ot my Tessy's doctors about the reactions to vac's and the sort they also didn't know or even heard of such a thing.  They all thought I was crazy till they started talking to specialists who said the same thing I was saying.  I can only assume the chances of a severe reaction are extremely small but they do happen.