calliecritturs
Posted : 11/12/2009 2:07:33 PM
BEVOLASVEGAS
His spleen is about 3 times the normal size, which is, apparently, somewhat normal with this disease. They did take a biopsy of it to make sure that spleen isn't the problem, but they don't believe that it is the cause.
The spleen takes a huge beating with IMHA -- it "stores" blood to a degree -- and when the body gets RALLY low it goes to the spleen FOR blood (which then irritates).
SO MANY things about this darned disease mimic cancer and other diseases. I can't tell you how many times they have started to treat some part of Billy's IMHA or some side effect and *cautioned* me "WEll this could be ______________ BUT we think it's just part of the IMHA"
BEVOLASVEGAS
On an upnote, if him still being alive wasn't enough, he did seem a little stronger when we picked him up this morning. He did raise his head & give me a little nub wag.
Interesting note -- after they get a transfusion they FEEL better -- hence he was feeling good enough to 'wag' a bit. And man, Billy's whole "how he was" got told by his tail.
But they have to get stuck SO many times with this -- but the good part is every time they get blood they feel better so they at least don't get scared to go to the vet. The trick is to slow down the darned immune system.
BTW - for those already going nuts from the acronyms:
AIHA = Auto-immune hemolytic anemia
and in most places now it is called:
IMHA -immune-mediated hemolytic anemia. But it's commonly known by both monikers = IMHA and AIHA
Bot vets and human doctors fall all over those terms "auto-immune" and "immune-mediated". There is a technical difference why some prefer the immune-mediated term (aparently "auto-immune" is almost an oxymoron of sorts)
In any event -- particularly for those of you wanting to pray and send good thots it may help you to know the whole 'deal" with this disease is that the body begins to turn against itself. The body simply begins to kill it's own red blood cells. A normal dog PCV (packed-cell volume) is about 35 - 50 (depends on the individual, breed, and many other things) So a PCV of 16 is danged low. 12 and below is often fatal,
So the whole goal is to get Brutus's body to lay off itself. pred is *always* the first drug they use (because it has the fastest response time actually) to give enough to suppress the immune system (to get it to lay off the body).
Some around here are only too familiar with the disease. Billy is an IMHA survivor. Willow and Pirate both had another immune-mediated-but-related disease "cytopenia" -- altho they were minorly different. the "cytopenias" have to do with platelets rather than red-blood cells.
Outdoorschik lost Snickers to them. Snickers had IMHA and was rallying, but then she got thrombocytopenia *with* IMHA -- which is even more difficult and she didn't make it.
So for those of you relatively new, that's why everyone has reacted the way they have. This is just the most heinous disease system.
Brutus -- we are pulling for you hon!!! *hugs*