Hi Folks... Oh no,,,,,,,,,,,,, a Great Dane with the runs is NOT GOOD! You know,,many times on this forum I answered questions about what to do with a dog with diarrhea,,,but now Bubby has it and I only have caplets... of course she who eats EVERYTHING,,,,doesn't like them. BUT I got one down her,,,but I can't see one for a Dane. We used to just pour out of the bottle, the liquid PB down Ollies throat,, (what a mess that was) but I just have caplets right now. IT says 2 for adults,,,should I give her two do you guys think? Or more? I don't know what is wrong with her. She had it a week ago after I gave her a rib bone,,with tons of meat on it...but that cleared up and she hasn't had anything to eat different then she usually has, and she has been fine. She ate dinner,,,and it started not long after. I did give her cooked veal on her kibble,,,its the first time she had veal.....it was on sale. She usually has beef, turkey or sometimes pork. Its like WATER coming out of her,,,I feel so sorry for her. BUT she sure wanted the peanut butter that I put on the PB caplet.