Lymphocytes that are usually present within the internal organs of the dogs turn out to be malignant and cause lymphoma cancer in dogs. Lymphoma cancer in dogs is also called as lymphosarcoma. When this lymphoma cancer is restricted to a particular organ then there are greater chances of recovery but when it starts affecting the spleen and bone marrow cells, then it is really difficult to cure it. This cancer in the dogs can be controlled and treated by chemotherapy or autologous and allogeneic stem cell transplantation. Some breeds of dogs such as Bulldog, Boxer, Chow Chow, Scottish terrier, Poodle, German Shepherd Dog, etc., are more susceptible to lymphoma cancer as compared to other dogs. These dogs should be regularly checked for the symptoms.