This is really tough for me. Cherokee's a great dog with a lot of life left in her, so if I died tomorrow, I really wouldn't want her PTS. But she's got behavioral problems (human AND dog aggression), allergies, and she gets depressed (doesn't eat well, gets restless) if I'm not around for more than a day or two, and gets severely depressed if I'm gone more than a week or so (stops eating all together, chews her feet to shreds, loses huge clumps of hair, etc). I really HOPE she'd get over that if I died, but if she didn't, then I guess the best thing would be to euthanize her. If she was fine without me, I know my Mom would keep her, but she's really not an animal-person anymore, I'm not sure it wouldn't be a huge burden for her, and I'm not sure Cherokee would do great with her.
I have three sisters that I'm really close to, but two have dogs Cherokee doesn't get along with (plus neither is exactly a "dog-person", and one has a toddler who scares Cherokee), and the third is well...not the most responsible pet owner on the planet (she tends to get animals and then pawn them off on others...i.e. Cherokee, my Mom's cat Tiger-Lily, a cockatoo we used to have, and her current pup will almost definitely end up with someone else at some point in the next 15 years...), plus she's having a baby and I think that sister + Cherokee + baby would be an absolute recipe for disaster.
Basically it's my Mom or euthanasia. Guess I should talk to my Mom about this at some point...
On an interesting note..if something happened to any of my sisters or my Mom, I'm quite sure I'd be the one to get their pets. Let's hope something doesn't happen to all four of them at the same time, because not only would I be out my whole family, I'd have 4 cats, 4 large dogs, and no place to live. 
lol