Wow -- that was a TON all in one day. Lyme vaccine is a huge vaccine, very prone to side effects. Bordatella is a "live" vaccine that can be difficult for some dogs. Adding the chemicals on top increased the burden.
There are several of us on here who have dogs who have had auto-immune diseases (pancytopenia and 'immune-mediated hemolytic anemia a/k/a IMHA) so we've learned to be ultra cautious (my Billy can't ever be vaccinated with ANYTHING ... literally for *any* reason ... EVER).
Right now, go look at your dog's gums. Are they more pale than normal? Press your fingertip on the gum and then release -- the color should snap right back in just a second, *not* in several seconds. Pale gums means the vet again NOW. Do not wait for Monday.
One of the side effects of vaccines and chemicals can be things that cause anemia and you might not find it otherwise. (Any time you see lethargy you need to be concerned about anemia.)
When you take your dog to the vet absolutely INSIST on bloodwork. Something like pancytopenia might not show up otherwise (that's when the body kills it's own platelets so there is nothing to 'clot' blood and internal bleeding can happen).
This is likely attributable to the Lyme shot -- but those other things can add to the mix. It is usually the adjuvant that causes the problem actually -- that's the 'stuff' in the shot that disburses the disease cells (which is what vaccines are) to the body so immunity can be formed. But once a dog begins to react to a vaccine, honestly ANY vaccines should be avoided, not just that one.
You may want to search on here for Kris Christine's posts and there are a LOT of posts on here about vaccines.
If you can get to a health store (something like Whole Foods or Wild Oats) that has a homeopathic department you may want to get homeopathic Thuja. (NOT Thuja oil but the little blue Boiron tubes). Give 4 pellets three or four times a day over the next 3 days and that will help the body process the vaccines better. It's not going to make it "all better" but it will help the body at least assimilate what's been given.
If you've never used homeopathics -- **don't** give with food. Homeopathics are sweet. Fold the pellets inside a piece of paper and crush with a spoon and just pour in the dog's mouth or let the dog lick it up (they really are pleasant -- not bad at all). They are meant to be absorbed into the mucus membranes of the mouth.
I would be giving Benedryl (the normal dose is 1-2 mg per pound of body weight given three times a day, but I would definitely give the TWO MG. dose now because of the obvious allergic reaction, pink skin, etc.) Just use regular plain Benedryl (not a 'cold' formula -- no Tylenol/acetaminaphen for dogs EVER). The capsules are 25 mg each -- so for the two mg dose a 50 pound dog needs four capsules (yes that IS the correct dose -- check any vet PDR or even call the emergency vet for confirmation of that dose) and yes give it at least two or three times today.
Yes, that will make the dog sleepy -- but dogs have faster metabolisms than we do, hence the bigger dose (and a too-small dose will do nothing). But it should help the dog deal with the allergic reaction until you can get it to your own vet.
Good luck -- let us know how it goes.